Description
Retatrutide is an investigational once-weekly triple-hormone receptor agonist (targeting GIP, GLP-1, and glucagon receptors) developed by Eli Lilly, showing unprecedented weight loss results in trials, with up to ~24% body weight reduction in 48 weeks. Currently in Phase 3 trials (TRIUMPH program), it is designed for obesity, type 2 diabetes, and related conditions, with potential FDA approval expected around summer 2026

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